Psoriatic Arthritis

Psoriatic arthritis is a systemic, degenerative disease defined by inflammation of the skin and articulations. Broadly speaking happens in the forty to fifty years of age group but could happen at any age and both men and women could equally be affected. It shares a lot of symptoms with many different arthritic conditions such as pain, inflammation of the joints and stiffness. The reason of psoriatic arthritis is not presently identified.

Psoriasis (a skin condition) and arthritis (articulation disease) appear at referent times of the patient's life. Commonly the skin affliction comes along some time before the joint affliction in about 80% of patients and, in most cases psoriasis predates arthritis by a few months to several years.

Psoriasis is a common disease of the skin with symptoms such as uneven reddened scaly skin and inflammation most typically around the regions of the knee joint, elbow joint, scalp, navel and genitalia. People who have been diagnosed as having psoriatic arthritis have both conditions and many more than 10% of the people with psoriasis will develop a linked up inflammation of the joints.

Psoriatic arthritis belongs to a grouping of arthritic conditions collectively addressed as "spondyloarthropathies" they share futures such as inflammation, other than the skin and joints, to the eyes, oral cavity, spinal column, intestines, lungs and several other organs. Such arthritis related conditions are Chrohn's disease, reactive arthritis or Reiter's syndrome, ulcerative colitis and ankylosising spondiylitis with a common disposition to cause inflammation of the spine.

While with psoriatic arthritis not a lot of the articulations will become inflamed, they are aching, swollen up and red-hot. At times the whole joints of the fingers or toes could become swollen and in a few cases inflammation of the tendons and cartilage could develop. Inflammation of the cartilage on the chest cavity wall that joints the ribs to the sternum can cause chest pains, as in the case of costochondritis.

The diagnosis of Psoriatic arthritis is established primarily on a finding of psoriasis and that of inflammatory symptoms of the spine and/or additional joints and organs. There is no science lab test to diagnose the condition. However, a hereditary marker, HLA-B27, detected in blood examinations in more than 50% of the sufferers is the tell mark of the condition in patients with arthritis of the spinal column.

X-ray pictures could assist to find of any joint alterations that are particular to psoriatic arthritis and not other arthritic conditions. RF factor, a protein antibody made by the immune system assists in differencing between psoriatic and rheumatic arthritis

The real cause of psoriatic arthritis is not known. However, combinations of immune, hereditary and environmental agents are suspected. For instance, there are some commonalities in patients with psoriatic arthritis: fall of the immune cells named helper T cells, various common genes other than HLA-B27 and certain infective and environmental factors.

Although no cure for psoriatic arthritis is accessible numerous treatment choices are. These are for the most part centered in containing symptoms and prevent harm to joints.

* Disease-modifying anti rheumatic drugs (DMARDs) to assist in prevention of joint damage.

* Nonsteroidal anti-inflammatory drugs (NSAIDs) to control pain.

* UVB or PUVA light treatment under the supervision of a skin doctor

* NF-alpha inhibitors to block up inflammation

* Surgical procedure (seldom) once other treatments fail to alleviate symptoms.